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May aid in healing of intestinal anastomoses and fistulas, and shows benefits in models of inflammatory bowel disease, Crohns disease, and ulcerative colitis235
Patients who are pregnant or nursing are also excluded
Although dysfunction of the valves in leg veins is the typical cause of increased venous blood pressure, other factors can also contribute, including obstruction of the veins (eg, by blood clots) and decreased contraction of calf muscles (eg, due to leg immobility)
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