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Adding vitamin B12 does not usually change the semaglutide dose but may improve energy levels for some users

Some GPs may incorrectly believe that only patients with a definite diagnosis of PA, those with a positive intrinsic factor antibody test, require treatment for life so seem to be using this as their treatment exclusion criteria

This allows for a sufficient trial length and will allow for enough B12 to make a difference over a sustained period of time