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Initially developed for type 2 diabetes, these agents are increasingly used for weight management, with landmark trials such as STEP and SELECT demonstrating double-digit weight loss and reduced risk of major cardiovascular events
The underlying mechanism of selective insulin resistance has not been established but several hypotheses have been suggested
* Indicates that the p -value was calculated based on the final and baseline values of participants in the TRF group because no comparison was made between changes in values in a TRF group and a normal diet control group in the original manuscript
Our work provides an alternative strategy by combining dual-path synthesis with energy metabolism regulation and precursor feeding to improve GSH production
Assessment of Cell Viability ARPE-19 cell viability was evaluated by performing the 3-(4,5-dimethylthiazol-2-yl)5-(3-carboxymethoxyphenyl)2-(4-sulfophenyl)2 H-tetrazolium (MTS) assay as previously described [25]
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