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improvement in kidney outcomes Harm End Points: Severe hypoglycemia Narrative: Diabetes increases the risk for myocardial infarction, ischemia, arrhythmia, heart failure, retinopathy, neuropathy, and end-stage kidney disease
Important safety considerations include risks of pancreatitis, gallbladder disease, worsening of diabetic retinopathy (particularly with rapid improvement in blood glucose), and potential kidney injury if dehydration occurs due to gastrointestinal side effects
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Discover the Power of Alpha-Lipoic Acid for Enhanced Wellness
In subsequent studies glucagon was shown to induce lipolysis in healthy human volunteers, patients with type 1 diabetes, mice and rats with STZ-induced diabetes, adipocytes isolated from diabetic and non-diabetic animals 46 and, in agreement with our results, in human adipocytes from healthy volunteers 47
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