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In cisplatin-induced AKI, the reduction in miR-155 levels attenuates TEC apoptosis and DNA damage by upregulating telomeric repeat binding factor 1 (TRF1) and cyclin-dependent kinase 12 (CDK12), ultimately preventing telomere dysfunction and genomic DNA damage [98]
Using sterile water without preservative reduces shelf life to 24-48 hours maximum
Cruciferous Vegetables: Broccoli, kale, cauliflower, and Brussels sprouts
3), we monitored the presence of LC3-positive autophagosomes in cells depleted of TBC1D9B, ARL8A/B, or both proteins