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Metformin and prostate cancer: a new role for an old drug

A total of five botanical drugs and 3 polyherbal formulations have been included and summarized

GLP-1 receptor agonists mimic the gut hormone GLP-1 to stimulate insulin secretion, suppress glucagon, slow gastric emptying, and reduce appetite

Harmony Outcomes and SELECT trials only significantly reduced non-fatal MI using abliglutide and semaglutide, respectively [16, 22]

Its foundational mechanismscentered on VEGFR2 activation and systemic cytoprotectionprovide a compelling scientific basis for its observed benefits in both gastrointestinal healing and central nervous system stabilization