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Classification and structure The superfamily of the glutathione transferases are divided into at least four major families of proteins, namely cytosolic or soluble GSTs, mitochondrial GSTs, microsomal GSTs and bacterial fosfomycin-resistance proteins [39], [6], [69]

Glutathione adduct of methylmercury activates the Keap1-Nrf2 pathway in SH-SY5Y cells

doi: 10.1007/s00217-016-2650-z 30 Escobedo-HinojosaW

However, the detoxification pathways of erucin-nitrile and SFN-nitrile are poorly studied (the question marks in Figure 2)

This bidirectional effect, scientists call it buffering , is probably the key to its protective profile