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However, as explained by the Alzheimers Drug Discovery Foundation in 2024, while urolithin A does have an impressive safety profile, its long-term safety has yet to be established.4 Also, while rare, some people can be allergic to pomegranates, which are rich in the polyphenols that are metabolized into urolithin A.21 This doesnt necessarily mean that those with pomegranate allergies will have a reaction to urolithin A supplements, but it could be something to keep in mind
Highest documentation standard: FDA-registered manufacturers (Hospira, Fresenius Kabi) with per-lot COAs, NDC-traceable product, and cGMP manufacturing
Separate them by 12 hours minimum
This individualized approach allows ALA therapy to contribute to more stable long-term outcomes
