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Endogenous GLP-1 acts in GLP-1Rs located in this region and reduces the intake of highly palatable foods by suppressing mesolimbic dopamine signaling, which controls the pleasure-directed acquisition of food [24]

As a glucagon-like peptide-1 (GLP-1) receptor agonist, it primarily reduces cardiovascular risk by improving glycemic control in individuals with type 2 diabetes

They were contacted and were given the Global Response Assessment questionnaire to evaluate the patients perceptions of treatment effectiveness.64 (Peters et al., 2008) See Table 1 for the Global Response Assessment Scale

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Regulators have not yet completed their review, and it is not approved for routine use