There are currently ongoing observational studies and early-phase clinical investigations of BPC-157 in gastrointestinal disease, reflecting the strength of the gut healing literature and the relative accessibility of GI endpoints in human trials
If anything, most studies seem to trend towards higher B12 levels being protective
TB-500 is derived from thymosin beta-4, a naturally occurring peptide involved in actin cytoskeleton regulation and cellular movement, which makes it useful in studies examining cytoskeletal organization and cell motility
Clinically significant vitamin B 12 deficiency and megaloblastic anemia are unlikely, unless these drug therapies are prolonged for two or more years, or if in addition, the person's dietary intake is below recommended levels
Sensitivity analyses included a mixed-effects model for repeated measures and exclusion of post-baseline data from non-adherent participants to confirm robustness