A European Medicines Agency safety review concluded that semaglutide exposure may be associated with approximately a two-fold increase in the relative risk of NAION among adults with type 2 diabetes, translating to roughly one additional case per 10,000 treated patients annually
Additional strategies under investigation aim to develop small-molecule GLP-1R modulators, sustained-release depot formulations, and combination regimens that pair GLP-1R agonists with complementary agents to maximise metabolic and organ-protective benefits
Methods Trial design This cognitive evaluation was an exploratory study of the IIH:Pressure trial
Bright Red Tongue Possible Causes: Vitamin B12, folate, or iron deficiency (smooth, beefy tongue) Kawasaki disease (in children) Scarlet fever Fever or infection Clinical Insight: Consider checking CBC, iron studies, and vitamin levels
The authors found that the drumstick leaf and amaranth leaf powders increased retinol by 9 percent and 5 percent (respectively) and increased vitamin C by 44 percent and 6 percent (respectively)