The mouse intestinal L-cell line, STC-1, was cultured in 1648 medium containing 10% fetal bovine serum
Animal data shows systemic effects via oral and intragastric routes, suggesting mucosal absorption is possible, but nasal spray bioavailability for BPC 157 specifically has not been quantified in published research
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However, invariably, they failed to provide significant symptomatic benefit in phase 2 studies and no agent progressed into phase 3 studies (104)
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