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The fibrotic process is a dysregulated wound-healing response, driven by the persistent activation of fibroblasts (or myofibroblasts), which results in the deposition of excessive extracellular matrix (ECM) proteins such as collagen [4], a key feature of pathological tissue remodelling in fibrotic disorders [5,6,7,8]
Department of State
Phil Trans R Soc B: Biol Sci (2017) 372:20160219
Upon initiation of a GLP-1 RAs and during up-titration, it is advisable for cardiologists to counsel their patients to take smaller meals, eat slowly and stop before feeling full, and avoid fatty or spicy foods ( 4 Conclusion GLP-1 RAs seem to emulate the evolution of statins and sodium-glucose co-transporter-2 inhibitors in terms of being approved for indications other than their initial indication and becoming promising agents in CV medicine which will continue to grow
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