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Further data supporting the efficacy of this class of drugs are awaited from two similar ongoing phase III clinical trials: NCT02147925 aims to compare the change of intrahepatic lipids (IHL) in type 2 diabetic patients with non-alcoholic fatty-liver disease after a 26-week treatment of liraglutide, sitagliptin, or insulin glargine per day combined with metformin, while NCT02365233 will assess a similar outcome comparing pioglitazone to DPP-4 inhibitors (sitagliptin or saxagliptin) to insulin glargine
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Symptoms may include right upper abdominal pain, fever, nausea, vomiting, or jaundice, and require prompt medical assessment
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