B12 is safe on its own, but a few conditions call for extra care, which is why a provider reviews your history before treatment: Leber's hereditary optic neuropathy, a rare inherited eye condition, where certain forms of B12 may be a concern for the optic nerve
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Homocysteine level is a more direct measure of the function of vitamin B12 and folic acid (compared to red blood cell or serum testing)
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A B12 injection is a fast, focused way to top up that single nutrient, delivering it straight into the muscle where it is steadily absorbed and put to work