Because conditions of testing (e.g., patient samples, investigators, doses of the treatments administered and compared, outcome measures, etc.) vary among trials, it is virtually impossible to distinguish a difference in drug effect from a difference due to one of the confounding factors just enumerated
Bowen AR, McCalmont TH
The essence of this is to avoid for example
Description Wegovy (semaglutide) injection 1.7 mg or 2.4 mg and Wegovy are prescription medicines used with a reduced calorie diet and increased physical activity to: reduce the risk of major cardiovascular events such as death, heart attack, or stroke in adults with known heart disease and with either obesity or overweight
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