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A flexible segment in DPP-4 connects the transmembrane domain to the extracellular domain and is the target of shedding, a process in which the enzyme is cleaved and released into circulation [22]

These reductions were attributed primarily to decreased appetite, lower food cravings, and reduced energy intake, aligning with earlier findings in animal models

Effects of glucagon-like peptide-1 receptor agonists on incidence of hepatocellular carcinoma and liver decompensation in patients with diabetes: a systematic review and meta-analysis