Mallick B, Shrama DJ, Siddappa P, et al
Last reviewed: July 18, 2026 Last updated: July 18, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
doi: 10.1016/j.clinthera.2022.12.006 48
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Before starting retatrutide whether in a trial or, in future, as a licensed medicine the following topics should be discussed with your doctor: Your full medical history , including any personal or family history of thyroid cancer, pancreatitis, gallbladder disease, cardiovascular conditions, diabetic retinopathy, or gastrointestinal disorders such as gastroparesis Current medications : Retatrutide may interact with insulin or other antidiabetic agents, potentially increasing the risk of hypoglycaemia