Kato S, Funakoshi H, Nakamura T, Noma S, Kanai M, Ohya-Shimada W, et al
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Disodium edetate (minimal amount in March B12 injection) Disodium edetate is used in B12 injections as a chelating agent to help stabilize the formulation and enhance the absorption of trace minerals like zinc, manganese, and copper, which are often included alongside vitamin B12 for supplementation
Store the reconstituted solution at 28C and use within 28 days
The meta-analysis reported an odds ratio of 28.04 for injection site reactions compared to placebo