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In neurons, Grx has a protective effect on redox-sensitive enzymes and ion channels, meaning that its dysfunction is implicated in several neurodegenerative disorders involving protein misfolding and redox signaling dysregulation (Ogata et al., 2021)

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Eur J Clin Invest 25 : 176181

The role of amino acid transporters in GSH synthesis in the bloodbrain barrier and central nervous system