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Analysis of 14 paired liver biopsies revealed significantly lower baseline peripheral mtDNA copy number in NASH versus simple steatosis patients, establishing an association between mitochondrial dysfunction and disease severity
The oocytes were equilibrated in an equilibration medium containing 3% BSA and 10% EG for 3-5 min
Protective treatment approaches aimed at restoring the NADH/NAD ratio also include increasing flux to parallel pathways such as the pentose phosphate pathway [57, 70], Krebs cycle (TCA) and oxidative phosphorylation (Fig
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