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Semaglutide-specific considerations Semaglutide has among the lowest clinical trial injection site reaction rates at 1.4%, making it one of the best-tolerated GLP-1 agonists in this regard
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*In clinical trials studying Wegovy (2.4 mg), the average weight loss was 15% and 20%, respectively, when paired with diet and exercise (compared to 2.4% and 3.1% with diet and exercise alone)
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