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The Foundation: GLP-1 Receptor Agonism Endogenous GLP-1 is an incretin hormone secreted by the L-cells of the intestine in response to nutrient ingestion
At therapeutic doses (2.5 mg and above), this dual activation works as intended
July 5, 2024
The HMGCS2 gene is located on chromosome 1p12 and is composed of 10 exons that generate two alternatively spliced mRNAs, both of which encode distinct protein isoforms (isoform 1 is 508 amino acids and isoform 2 is 466 amino acids)
PMCID: PMC7442397
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