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A few nAChRs, particularly 7nAChRs, exhibit a significant permeability to Ca2+ [18]
Steady-state levels are achieved when the amount of the drug in your body stays constant because you are taking it at the same rate that your body is removing it
One in vitro study appears to suggest the half-life of DSIP to be around 15 minutes, while animal studies suggest 4-5 minutes
The overlapping mechanisms create risk of excessive sedation and respiratory depression
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