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Metformin has long been associated with cardiovascular benefits based on the UKPDS trial data and observational studies, suggesting a 10-15% reduction in cardiovascular events
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J Am Acad Dermatol
INDIANAPOLIS A clinical trial led by an Indiana University School of Medicine researcher found that weekly doses of semaglutide a medication typically prescribed to Type 2 diabetes patients improved blood sugar levels and weight loss for adult Type 1 diabetes patients who use automated insulin delivery systems and have a body mass index of 30 or higher
Supporting this, Wu et al [35] described islet infiltration by CD8 + cytotoxic T cells and macrophages in type 2 diabetes, likely driven by chronic hyperglycaemia and hyperlipidaemia [36]
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