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More visible and consistent results typically occur after reaching a higher therapeutic dose in subsequent months
Cold Spring Harb Symp Quant Biol
TRIUMPH-4 Phase 3 (68 weeks, 12mg): 28.7%
Functions of the Gallbladder
The landmark FLINT trial demonstrated that treatment with the FXR agonist obeticholic acid (OCA) led to significant reductions in liver fat content and was associated with histologic improvement in patients with nonalcoholic steatohepatitis (NASH) (88)
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