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Data availability The data underlying this article are available in NAHNES website, at [ Abbreviations ASCVD: Atherosclerotic cardiovascular disease BMI: Body mass index BRC: Biomedical Research Centre CAD: Coronary artery disease CDC: Centers for Disease Control and Prevention CI: Confidence interval CKD: Chronic kidney disease CKD-EPI: Chronic Kidney Disease Epidemiology Collaboration CVD: Cardiovascular disease eGFR: Estimated glomerular filtration rate FDA: Food and Drug Administration GLP-1: Glucagon-like peptide-1 GLP-1 RA: Glucagon-like peptide-1 receptor agonist HbA1c: Glycated haemoglobin HR: Hazard ratio IQR: Interquartile range KDIGO: Kidney disease: improving global outcomes MACE: Major adverse cardiovascular events MEC: Mobile Examination Center MI: Myocardial infarction NCHS: National Center for Health Statistics NHANES: National Health and Nutrition Examination Survey NIHR: National Institute for Health and Care Research NNT: Number needed to treat PAD: Peripheral artery disease SOUL: Semaglutide Cardiovascular Outcomes Trial U.S.: United States UK: United Kingdom References Zhou B, Rayner AW, Gregg EW, Sheffer KE, Carrillo-Larco RM, Bennett JE, et al

My advice is always the same - build a strong lifestyle foundation of quality, whole food, high fiber, strong protein, and resistance training first

After about 21% initial loss, participants who continued lost another 5.5%

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