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Deficiency of heme oxygenase 1a causes detrimental effects on cardiac function
When taken orally, this protein gets broken down into its amino acids, just like any protein molecule, so studies show the complete antioxidant doesnt really make it out of digestion intact
Animal tissues with high lipoyllysine content (~1-3 g/g dry wt) include kidney, heart, and liver, while lipoyllysine-rich vegetables include spinach and broccoli (107)
Senescent cells are cells that have permanently halted their cell cycle ('replicative arrest') but resist apoptosissometimes called 'zombie cells.' They accumulate with age in multiple tissues and secrete a pro-inflammatory cocktail called the Senescence-Associated Secretory Phenotype (SASP), containing IL-6, IL-8, MMP-3, MMP-9, TNF-, and other factors that damage surrounding healthy tissue
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