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Striking the balance: GLP-1/glucagon co-agonism as a treatment strategy for obesity

Potential side effects: Though peptide therapy is safe, it may cause side effects in some people, such as injection site reactions or hormonal imbalances

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Common side effects and contraindications (bullet list): Mild injection-site redness, bruising Increased hunger, flushing, water retention Headache, dizziness, nausea Temporary joint discomfort Contraindications: active cancer, uncontrolled diabetes, pregnancy, certain cardiac conditions Long-Term Effects Long-term use of CJC-1295, either alone or in combination with peptides such as Ipamorelin, may cause persistent changes in hormones impacting reproductive health and aging

Campello CP, Lemos CAA, Andrade WTL, Melo LPF, Nunes GRS, Cavalcanti HG