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The first bioreversible prodrug of metformin with improved lipophilicity and enhanced intestinal absorption
This procedure involved removing the supernatant and resuspending the mitochondrial pellet in an isolation buffer of 250 mM sucrose, 0.5 mM EDTA, and 10 mM Tris-HCl to achieve a final protein concentration of 20-25 mg/ml [2]
The mean differences between left and right thalamic GSH were small and non-significant in all groups (HC: p = 0.570
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