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Plateaus are normal and do not necessarily mean treatment has failed

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Deciding between the two will depend on individual health profiles, weight loss goals, and the guidance of healthcare providers

Before combining medications, discuss optimizing your current therapy by ensuring adequate dosing and treatment duration, exploring FDA-approved alternatives like tirzepatide or phentermine-topiramate ER, intensifying lifestyle interventions with behavioral therapy, or considering metabolic surgery if you meet clinical criteria

Cefalu WT, Buse JB, Del PS, et al