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Robinson, D.S., Hamid, Q., Bentley, A., Ying, S., Kay, A.B., Durham, S.R., Activation of CD4+ T cells, increased Th2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma, J

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So it both calls in the development of new vasculature and it promotes the growth of that new vasculature

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Starting with the lowest possible dose means any initial side effects are likely to be milder and more manageable