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Prioritizing protein content, fat, calorie, and sugar reduction while boosting the nutritional value of products will be essential to support GLP-1 usage for weight reduction
Still extraordinary
Sci Transl Med 2018;10(467)
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Over time, a patient (under the guidance of their practitioner) may gradually increase their dose up to a maximum of 2.4mg, depending on each persons individual response to the medication
Research mechanism GLP-1 receptor activation in pancreatic -cells, hypothalamus, brainstem Glucose-dependent insulin secretion Delayed gastric emptying Central appetite suppression via hypothalamic and brainstem receptors Trial data summary STEP 1 trial (Wilding et al., NEJM 2021): mean body weight reduction of 14.9% at 68 weeks with weekly 2.4mg dosing
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