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The safety profile of GLP-1 medications as a class is well established
Understanding their mechanisms of action provides crucial insights into their comparative efficacy and potential applications in clinical practice
| Korean CosWorld Bangladesh
In women with PCOS, high concentrations of leptin have been reported to inhibit the expression of aromatase mRNA in granulosa cells, while the hyperandrogenic follicular environment in GCs was found to significantly reduce the expression of P450arom, which can convert androgens into estrogen, further increasing the levels of androgens and ultimately promoting follicular atresia (148150)
Risk: Strongly associated with atherosclerosis, coronary heart disease, and Alzheimers disease
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