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Presented at ACR Convergence 2025, Chicago, IL
Ipamorelin is a 5-amino acid peptide that mimics ghrelin, the hunger hormone. It binds to ghrelin receptors (GHS-R) to stimulate a rapid spike in growth hormone release, without affecting cortisol or prolactin levels
Compounded Ipamorelin preparations, historically mixed by some compounding pharmacies for patient dispensing, sit in a separate category that Health Canada has flagged through its unauthorized-peptide enforcement notices
The lack of human data means we are extrapolating safety from horses to humans, a leap that rarely holds up perfectly in clinical practice
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