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For example, in breast cancer (BC) patients, HMGB1 expression serves as an effective indicator of the immunogenicity and efficacy of chemotherapeutic agents, and elevated levels of HMGB1 have been associated with improved clinical outcomes in patients receiving neoadjuvant chemotherapy [305]
J Clin Invest 111(5):607616
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xCT and other amino acid transporters, such as L-type amino acid transporter 1 (LAT1) and LAT2, are potential therapeutic targets due to their availability and pharmacological properties
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