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The failure of the Exenatide-PD3 and NLY01 trials has cast serious doubt on whether GLP-1 RAs have a future in PD
The main practical disadvantages are: poor absorption in standard capsule form, the need for consistent daily use over 8-12+ weeks before visible results, relatively higher cost for well-absorbed formats, mild and uncommon side effects like digestive discomfort or headache in some users, and the risk of unrealistic expectations from aggressive marketing claims
For obesity trials, however, it can miss a crucial question: Where are the patients actually located
First introduced as an anticonvulsant for the treatment of epilepsy, gabapentins therapeutic scope has expanded considerably due to its efficacy in managing various types of neuropathic pain and other conditions
These are topline figures from the company, not the full published data, and retatrutide isnt approved anywhere yet
