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In a JAMA, researchers analyzed a wide population of people with type 2 diabetes and reported that GLP-1RA drugs do not increase the risk of pancreatic cancer compared to basal insulin over a 7-year period
10.1080/10408398.2011.640757 Crit Rev Food Sci Nutr
This effect stems from weight loss itself combined with possible direct vascular effects
(c) nuclear translocation of predominantly p65/p50 dimers to induce transcription of target genes, including well-established FLICE-like inhibitory protein (c-FLIP) and apoptosis protein inhibitors (c-IAP)
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