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Yingzi Cong teams research shows that whether administered systemically or locally, butyrate inhibits HDAC in a dose-dependent manner, inhibiting the GATA3 gene, reducing the number of Group 2 innate lymphoid cells (ILC2), lowering the concentration of IL-5, IL-13 cytokines, and improving AHR and Eosinophil-induced airway inflammation, all of which alleviate allergic asthma