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Based on this hypothesis, GH, made by pituitary glands, regulates somatic growth by controlling the production of hepatic IGF-I (or somatomedin C), which is then distributed through the circulation to act on remote target organs/tissues (2)
The most significant weight loss occurs after 12 to 16 weeks of consistent use
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Some protocols may use post-workout timing to maximize nutrient partitioning to muscle tissue
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