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Daungkamon Nokinsee et al
Reactive oxygen and nitrogen species in pathogenesis of vascular complications of diabetes
Ironically, a side effect of excessive anticholinesterase treatment is excessive weakness or cholinergic crisis due to excessive stimulation of nicotinic receptors in the muscle end-plate region, resulting in a transient phase of uncontrolled muscle fasciculations due to sustained depolarization, followed by the development of receptor desensitization and a flaccid paralysis
PHA: PHA (polyhydroxy acid) is similar to alpha hydroxy acids (AHAs) such as glycolic acid and lactic acid, but is considered to be gentler on the skin
The progress varies depending on diet, activity level, and individual response to the medication
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