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Comparison with other GLP-1s As compared to other GLP-1RAs, orforglipron is a direct and orally active small molecule, rather than a peptide
The TPO receptor agonist regulates blood platelet production by binding to and activating TPO receptors on megakaryocyte cells and inducing signalling cascades that increase platelet production
Lancet (2019) 394:3950
Statistical analysis was performed using GraphPad Prism software, and Adobe Illustrator was used to compile figures for presentation
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