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(35) Conclusion GLP-1 receptor agonists are becoming integral to obesity and diabetes management, with significant implications for orthopedic surgery

While the RNI for maintenance is only 1.5 g daily, therapeutic oral doses typically range from: 50-150 g daily for mild deficiency prevention in at-risk groups 1,000-2,000 g daily for treating confirmed deficiency without malabsorption Some formulations contain up to 5,000 g, though there is no proven additional benefit over 1,000-2,000 g for most patients The reason for this dosage discrepancy lies in absorption efficiency

It also enhances metabolism and aids in weight control, making it an essential ally in neurophatic care

How does Cagrilintide differ from GLP-1 drugs like semaglutide