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Another study conducted by Fang and colleagues highlighted that CD44-overexpressing 4T1 breast cancer cells showed significantly better cytotoxic response to docetaxel-loaded multifunctional hyaluronic acid nanoparticles as compared to free docetaxel [222]
19 High tumor mutational burden (TMB), 20,21 microsatellite instability (MSI-H), 22 and mismatch repair deficiency (dMMR) 23 are associated with enhanced neoantigen presentation and improved responses to immune checkpoint inhibitors (ICIs)
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This is something that individuals and employers may want to consider before opting to use or fund GLP-1 drugs for weight loss
