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After feeding all branching pathways, the excess of glycolytic flux is converted to lactate to preserve a sufficient pool of NAD+ for glycolysis and also to avoid the tricarboxylic acid (TCA) cycle inhibition due to excess NADH

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Studies have demonstrated that salidroside significantly reduces airway inflammation and oxidative stress in asthmatic models by decreasing the levels of pro-inflammatory cytokines such as IL4, IL5, and IL13, while increasing the levels of anti-inflammatory cytokines, such as IFN and IL10, in bronchoalveolar lavage fluid [226]

J Biomed Sci