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These data represent the first demonstration of self-delivery of an evolved BoNT protease targeting a non-SNARE substrate in cancer cells
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Non-Pharmaceutical Options Lifestyle interventions Structured diet plans, regular physical activity, and behavioural therapy
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[1] Licensed pharmacological options in the UK include orlistat (available at BMI 30 kg/m, or 28 kg/m with weight-related risk factors) and semaglutide (available within specialist weight management services as per NICE TA875, with adjusted BMI thresholds for some ethnic groups)
It functions by stimulating the release of specific hormones that play a crucial role in regulating ovulation
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