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WSJ reports that, while drugs like Wegovy and Zepbound arent approved for kids under 12, some doctors believe prescribing GLP-1s off-label to children with obesity can help them reduce their Body Mass Index (BMI) and reduce their risk of obesity-related, lifelong issues like Type 2 diabetes and high blood pressure
Diabetes, oncology, respiratory diseases, and neurology remain dominant segments
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Lancet 378:584594 Hustad S, Ueland PM, Vollset SE, Zhang Y, Bjorke-Monsen AL (2000) Riboflavin as a determinant of plasma total homocysteine: effect modification by the methylenetetrahydrofolate reductase C677T polymorphism
Data from an early meta-analysis of 18 trials provided evidence that in people living with T2DM, GLP-1 RAs promote a mean weight loss of 2.8 kg ( 3.4 to 2.3 kg) [116]
