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observed that APS stimulate KCs by decreasing the amounts of recombinant autophagy-related proteins (ATGs), family members (ATG7, ATG12, and ATG6), and protein II light chain 3 (LC3II), resulting in a decrease in CD68-positive KCs (Martinez-Lopez and Singh, 2015
The side effects are temporary and usually subside within 23 days
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Through these mechanisms, HSP70 and HSP90 reduce the formation of neurofibrillary tangles, thereby mitigating one of the core pathological processes underlying tau-mediated neurodegeneration
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