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May decrease the absorption of oral vitamin C supplements, requiring dosage adjustments
ADU selectively binds to A fibrils and soluble oligomers, which reduced amyloid plaques in a dose-dependent and time-dependent manner ( Box 2 )
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In this way, it serves as a proofofconcept that even a peptide or protein drug known to have poor bioavailability can still be delivered orally, and without any modification, if we compensate by delivering a sufficiently high dose
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