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Approved GLP-1 Agonists for Weight Loss Currently, there are two GLP-1R agonists approved for the treatment of obesity, Saxenda (liraglutide) and Wegovy (semaglutide) , both developed by Novo Nordisk and approved by the FDA in 2014 and 2021, respectively

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Gastrointestinal Tolerability of Oral Versions Stomach upset ranks among the most common side effects of GLP-1 therapy